Pathology of the Developing Mouse: A Systematic Approachآسیب شناسی موش در حال توسعه: یک رویکرد سیستماتیک

Books Pathology of the Developing Mouse: A Systematic Approach

کتاب آسیب شناسی موش در حال توسعه: یک رویکرد سیستماتیک را از فروشگاه اینترنتی ایران وت بوک تهیه فرمایید.

Sections:

1. The Case for Developmental Pathology and Developmental Pathologists
2. Essentials of Mouse Genetics and Nomenclature
3. Essential Terminology for Mouse Developmental Pathology Studies
4. Anatomy and Physiology of the Developing Mouse and Placenta
5. Teratogens and Teratogenic Mechanisms in Mouse Developmental Pathology
6. Principles of Experimental Design for Mouse Developmental Pathology Studies
7. Necropsy Sampling and Data Collection for Studying the Anatomy, Histology, and Pathology of Mouse Development
8. Clinical Pathology Analysis in Developing Mice
9. Histotechnological Processing of Developing Mice
10. Localization of Gene Expression in Developing Mice
11. Protein Localization in Developing Mice
12. Quantitative Morphological Assessment in Mouse Developmental Pathology Studies
13. Ultrastructural Evaluation of Developing Mice
14. Three-Dimensional Imaging in Mouse Developmental Pathology Studies
15. Pathology of the Developing Mouse from Conception to Weaning
16. Pathology of the Placenta
17. Mouse Developmental Pathology Assessments in High-Throughput Phenogenomic Facilities
18. A Statistical Analysis Primer for Mouse Developmental Pathology Studies

Description:

Pathology of the Developing Mouse provides, in so far as feasible, one complete reference on the design, analysis, and interpretation of abnormal findings that may be detected in developing mice before and shortly after birth. In particular, this book is designed specifically to be not only a “how to do” manual for developmental pathology experimentation in mice but, more importantly, a “how to interpret” resource for pathologists and other biomedical scientists faced for the first or hundredth time with defining the significance of distorted features in some fantastic murine developmental monstrosity.

The topics covered in this volume include a full range of subjects encountered when building and wielding a developmental pathology tool kit:

baseline anatomic and physiologic traits of developing miceprinciples of good experimental design and statistical analysis for mouse developmental pathology studiesprocedures for anatomic pathology examinations, to evaluate structural changes at the macroscopic (gross), microscopic (cells and tissues), and ultrastructural (subcellular) levels, suing conventional autopsy-based or novel non-invasive imaging techniques;methods for clinical pathology testing, to assess the biochemical and cellular composition of tissues and fluids;options and protocols for in situ molecular pathology analysis, to undertake site-specific explorations of the various mechanisms responsible for producing adverse findings (i.e., “lesions”) during development; andwell-referenced and illustrated guides to the interpretation of anatomic pathology and clinical pathology changes in the animal (embryos, fetuses, neonates, and juveniles) and its support system (placenta).